Description

3-(3,4-Dimethoxyphenyl)-2-Methyl-L-Alanine Hydrochloride is a high-purity, non-natural amino acid derivative used as a critical chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecules with specific stereochemistry, essential for pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Peptidomimetics & Bioactive Molecule Design: Used to incorporate constrained, non-proteinogenic amino acid motifs into peptides and peptide-like compounds to enhance stability, bioavailability, and receptor selectivity.
• Agrochemical Research: Serves as a building block for developing advanced, chiral active ingredients with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Utilized to create labeled or modified amino acid analogs for studying biological pathways and protein function.
• Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.

Basic Information

Product Name	3-(3,4-Dimethoxyphenyl)-2-Methyl-L-Alanine Hydrochloride
CAS No.	5486-79-3
Molecular Formula	C₁₂H₁₇NO₄·HCl
Molecular Weight	275.73 g/mol
Synonyms	L-3-(3,4-Dimethoxyphenyl)-2-methylalanine hydrochloride; (2S)-2-Amino-2-methyl-3-(3,4-dimethoxyphenyl)propanoic acid hydrochloride; 2-Methyl-3,4-dimethoxy-DL-phenylalanine hydrochloride (related); 3,4-Dimethoxy-2-methylphenylalanine HCl; 5486-79-3; Veratrylalanine hydrochloride derivative
EINECS	Contact for details

Quality Control

Our 3-(3,4-Dimethoxyphenyl)-2-Methyl-L-Alanine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.