Description

2-Chloroquinoline-4-Carboxylic Acid is a versatile and high-value heterocyclic building block in organic synthesis. Its core value proposition lies in its bifunctional structure, featuring both a reactive chlorinated quinoline ring and a carboxylic acid group, enabling diverse chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a key intermediate in the development of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various quinoline-based drug candidates, including potential antimicrobial, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the bioactive quinoline scaffold.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of novel organic electronic materials, dyes, and ligands for metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for constructing complex heterocyclic compounds via cross-coupling, hydrolysis, and cyclization reactions.
• Ligand Synthesis: The carboxylic acid and nitrogen atoms make it a useful starting material for synthesizing chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	2-Chloroquinoline-4-Carboxylic Acid
CAS No.	5467-57-2
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	2-Chloro-4-quinolinecarboxylic acid; 2-Chloroquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 2-chloro-; 2-Chloro-4-carboxyquinoline; 2-Chlor-4-chinolincarbonsäure (German); Acide 2-chloro-4-quinolinecarboxylique (French); 5467-57-2; 2-Chloroquinaldin-4-carboxylic acid
EINECS	226-764-8

Quality Control

Our 2-Chloroquinoline-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.