Description

4-Nitrophthalic Anhydride is a key nitrated aromatic anhydride intermediate valued for its reactive sites that enable further functionalization. This compound is essential for synthesizing advanced materials and fine chemicals where the nitro and anhydride groups serve as critical handles for downstream reactions. It is primarily sought by manufacturers in the pharmaceutical, agrochemical, and specialty dye industries for the production of complex organic molecules.

Application

• Intermediate in the synthesis of pharmaceutical active ingredients (APIs), particularly those with complex polycyclic structures.
• Key building block for the production of advanced agrochemicals, such as herbicides and plant growth regulators.
• Precursor for the manufacture of functional dyes and pigments, including optical brighteners and laser dyes.
• Starting material for the synthesis of monomers used in high-performance polymers and engineering plastics.
• Used in organic research and development for the preparation of novel heterocyclic compounds.
• Intermediate in the production of corrosion inhibitors and other specialty additives for industrial applications.

Basic Information

Product Name	4-Nitrophthalic Anhydride
CAS No.	5466-84-2
Molecular Formula	C8H3NO5
Molecular Weight	193.11 g/mol
Synonyms	4-Nitro-1,3-isobenzofurandione; 4-Nitrophthalic Acid Anhydride; 1,3-Dioxo-1,3-dihydroisobenzofuran-5-carboxylic acid, 5-nitro-; 5-Nitrophthalic Anhydride; 4-Nitro-1,2-benzenedicarboxylic Anhydride; 4-NPA; NSC 403116
EINECS	226-775-7

Quality Control

Our 4-Nitrophthalic Anhydride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets precise chemical and physical specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to guarantee batch-to-batch consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	160 - 165 °C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.