Description

2-(4-Chloro-Phenyl)-Quinoline-4-Carboxylic Acid is a high-purity organic chemical building block of significant commercial and research interest. This compound serves as a critical intermediate in the synthesis of advanced pharmaceutical agents and functional materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with quinoline-based structures for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for creating organic ligands, metal-organic frameworks (MOFs), and advanced polymers with specific electronic or photonic properties.
• Dye & Pigment Industry: Intermediate for the production of specialized quinoline-based dyes and colorants.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and exploratory synthetic chemistry in academic and CRO (Contract Research Organization) settings.
• Catalyst Development: Potential precursor for designing novel organocatalysts or metal-complex catalysts.

Basic Information

Product Name	2-(4-Chloro-Phenyl)-Quinoline-4-Carboxylic Acid
CAS No.	5466-31-9
Molecular Formula	C16H10ClNO2
Molecular Weight	283.71 g/mol
Synonyms	4-Chloro-2-phenylquinoline-4-carboxylic acid; 2-(p-Chlorophenyl)quinoline-4-carboxylic acid; 2-(4-Chlorophenyl)-4-quinolinecarboxylic acid; Quinoline-4-carboxylic acid, 2-(4-chlorophenyl)-; 5466-31-9; 2-(4-Chlorophenyl)quinoline-4-carboxylic acid; p-Chloro-2-phenylquinoline-4-carboxylic acid
EINECS	226-764-9

Quality Control

Our 2-(4-Chloro-Phenyl)-Quinoline-4-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) is provided with every shipment, and custom purity grades are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.