Description

4'-Chloro-3'-Nitroacetophenone is a versatile and high-purity organic intermediate of significant importance in fine chemical synthesis. Its unique molecular structure, featuring both chloro and nitro substituents on the acetophenone core, makes it a critical building block for the production of more complex molecules. This compound is essential for research and development laboratories and manufacturing facilities in the pharmaceutical and agrochemical sectors, where it serves as a key precursor for active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with complex aromatic structures.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, leveraging its reactive nitro and chloro groups for further functionalization.
• Dye and Pigment Manufacturing: Serves as a starting material for the production of specialized azo dyes and organic pigments due to its aromatic nitro compound properties.
• Organic Synthesis Research: Employed in academic and industrial R&D for exploring novel chemical reactions, such as nucleophilic aromatic substitution and reduction reactions.
• Liquid Crystal and Electronic Material Precursor: Can be utilized in the synthesis of advanced materials for electronic applications.

Basic Information

Product Name	4'-Chloro-3'-Nitroacetophenone
CAS No.	5465-65-6
Molecular Formula	C8H6ClNO3
Molecular Weight	199.59 g/mol
Synonyms	1-(4-Chloro-3-nitrophenyl)ethanone; 3'-Nitro-4'-chloroacetophenone; 4-Chloro-3-nitroacetophenone; 1-Acetyl-4-chloro-3-nitrobenzene; Ethanone, 1-(4-chloro-3-nitrophenyl)-; p-Chloro-m-nitroacetophenone; NSC 403119
EINECS	226-759-1

Quality Control

Our 4'-Chloro-3'-Nitroacetophenone is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.