Description

2-Amino-6-Ethylsulfanylcarbonyl-5,6,7,8-Tetrahydro-1H-Quinazolin-4-One is a specialized heterocyclic organic compound with the CAS number 5460-56-0, serving as a key advanced intermediate in modern synthetic chemistry. Its value lies in its functionalized quinazolinone core, which is integral for constructing complex molecular architectures with targeted biological activity. This high-purity intermediate is primarily required by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel quinazolinone-based drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe Synthesis: Employed in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands and organic compounds used in catalysis and advanced materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-Amino-6-Ethylsulfanylcarbonyl-5,6,7,8-Tetrahydro-1H-Quinazolin-4-One
CAS No.	5460-56-0
Molecular Formula	C11H15N3O2S
Molecular Weight	253.32 g/mol
Synonyms	2-Amino-6-(ethylthio)carbonyl-5,6,7,8-tetrahydro-4(1H)-quinazolinone; 6-(Ethylthio)carbonyl-2-amino-5,6,7,8-tetrahydro-4(1H)-quinazolinone; 2-Amino-6-[(ethylthio)carbonyl]-5,6,7,8-tetrahydro-4(1H)-quinazolinone; 4(1H)-Quinazolinone, 2-amino-5,6,7,8-tetrahydro-6-[(ethylthio)carbonyl]-; Ethyl 2-amino-4-oxo-1,4,5,6,7,8-hexahydroquinazoline-6-carbothioate; CAS 5460-56-0
EINECS	Contact for details

Quality Control

Our production of 2-Amino-6-Ethylsulfanylcarbonyl-5,6,7,8-Tetrahydro-1H-Quinazolin-4-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for research and scale-up activities. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.