Description

trans-2-Aminocyclohexanol Hydrochloride is a chiral amino alcohol derivative in its hydrochloride salt form, offering enhanced stability and handling properties. This compound serves as a critical chiral building block and resolving agent in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurological and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used to develop chiral ligands for transition metal catalysis, crucial for enantioselective hydrogenation and C-C bond formation.
• Chiral Resolving Agent: Employed for the separation of racemic mixtures of carboxylic acids and other acidic compounds via diastereomeric salt formation.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways in process chemistry.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.

Basic Information

Product Name	trans-2-Aminocyclohexanol Hydrochloride
CAS No.	5456-63-3
Molecular Formula	C6H13NO • HCl
Molecular Weight	151.64 g/mol
Synonyms	(1R,2R)-2-Aminocyclohexanol Hydrochloride; (1S,2S)-2-Aminocyclohexanol Hydrochloride; trans-2-Amino-1-cyclohexanol Hydrochloride; (±)-trans-2-Aminocyclohexanol Hydrochloride; 2-Aminocyclohexanol Hydrochloride (trans-); Cyclohexanol, 2-amino-, hydrochloride, trans-; 1,2-Cyclohexanediol, 2-amino-, hydrochloride (trans-); 2-Aminocyclohexyl Alcohol Hydrochloride (trans-)
EINECS	226-704-8

Quality Control

Our trans-2-Aminocyclohexanol Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.