Description

2,3-Dihydro-1H-Inden-5-Ylacetic Acid is a versatile carboxylic acid derivative of the indane scaffold, serving as a critical building block in advanced organic synthesis. Its unique structure makes it a valuable intermediate for the development of pharmaceuticals and fine chemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to create novel active molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), prostaglandin analogs, and other bioactive molecules targeting the central nervous system.
• Agrochemical Research: Used in the development of novel herbicides and plant growth regulators, leveraging its fused aromatic-aliphatic ring system.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the synthesis of specialty polymers and liquid crystals due to its rigid, planar core structure.
• Chemical Biology & Proteomics: Utilized as a scaffold or linker molecule in the design of enzyme inhibitors and molecular probes.

Basic Information

Product Name	2,3-Dihydro-1H-Inden-5-Ylacetic Acid
CAS No.	5453-98-5
Molecular Formula	C11H12O2
Molecular Weight	176.21 g/mol
Synonyms	5-Indanylacetic Acid; (2,3-Dihydro-1H-inden-5-yl)acetic Acid; 5-(Carboxymethyl)indane; 1H-Indene-5-acetic acid, 2,3-dihydro-; Indan-5-ylacetic acid; 2,3-Dihydroindene-5-acetic acid; 5-Indanacetic Acid
EINECS	226-704-5

Quality Control

Our 2,3-Dihydro-1H-Inden-5-Ylacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.