Description

Ethyl 3,3-Diphenyloxirane-2-Carboxylate is a high-value oxirane (epoxide) derivative characterized by its diphenyl-substituted structure. This compound serves as a versatile and critical chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Research: Used in the development of novel, optically active pesticides and herbicides where specific stereochemistry is crucial for bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & R&D Laboratories: Utilized in methodological studies and the exploration of new ring-opening and functionalization reactions of epoxides.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specific thermal or optical properties.

Basic Information

Product Name	Ethyl 3,3-Diphenyloxirane-2-Carboxylate
CAS No.	5449-40-1
Molecular Formula	C17H16O3
Molecular Weight	268.31 g/mol
Synonyms	Ethyl 2,3-Epoxy-3,3-diphenylpropionate; Ethyl 3,3-Diphenylglycidate; (±)-Ethyl 3,3-diphenyloxirane-2-carboxylate; Ethyl 3,3-Diphenyl-2-oxiranecarboxylate; trans-Ethyl 3,3-diphenylglycidate; Ethyl diphenylglycidate; Glycidic acid, 3,3-diphenyl-, ethyl ester; NSC 3349
EINECS	226-661-5

Quality Control

Our Ethyl 3,3-Diphenyloxirane-2-Carboxylate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess (if applicable), and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Chiral Purity (if specified)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.