Description

trans-2-tert-Butylcyclohexan-1-Ol is a high-purity, stereochemically defined cyclohexanol derivative, valued for its role as a key chiral intermediate and building block in advanced organic synthesis. Its rigid, bulky tert-butyl group adjacent to the hydroxyl function makes it an excellent ligand precursor and a valuable probe for studying steric and conformational effects. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty materials sectors seeking to introduce specific stereochemistry into complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing sterically hindered compounds.
• Asymmetric Catalyst Ligand: Used in the development and synthesis of novel chiral ligands for transition metal catalysis in enantioselective reactions.
• Agrochemical Synthesis: Acts as a building block for creating bioactive molecules with specific spatial configurations for crop protection agents.
• Fragrance & Flavor Chemistry: Employed in research to synthesize novel odorants and flavorants where the tert-butyl group contributes to unique olfactory properties.
• Material Science Research: Utilized as a monomer or modifier in polymer research to impart rigidity and influence polymer chain packing and properties.
• Organic Synthesis Standard: Functions as a reference standard and reagent in methodological development for stereoselective synthesis and kinetic studies.

Basic Information

Product Name	trans-2-tert-Butylcyclohexan-1-Ol
CAS No.	5448-22-6
Molecular Formula	C₁₀H₂₀O
Molecular Weight	156.27 g/mol
Synonyms	trans-2-(1,1-Dimethylethyl)cyclohexanol; 2-tert-Butylcyclohexanol (trans-); (1R,2R)-2-tert-Butylcyclohexan-1-ol; (1S,2S)-2-tert-Butylcyclohexan-1-ol; 2-tert-Butyl-1-cyclohexanol; 2-(tert-Butyl)cyclohexanol; NSC 403754
EINECS	226-654-1

Quality Control

Our trans-2-tert-Butylcyclohexan-1-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and physical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (trans-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.