Description

1,3-Ditrityloxypropan-2-Ol is a high-purity, protected diol derivative featuring trityl (triphenylmethyl) ether groups. This compound is a critical synthetic intermediate valued for its role in the selective protection of hydroxyl functionalities in complex organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for nucleoside analogs and complex polyol structures.
• Oligonucleotide & Peptide Synthesis: Serves as a versatile protecting group reagent for hydroxyl functions during solid-phase and solution-phase synthesis.
• Carbohydrate Chemistry: Used in the selective protection and manipulation of sugar alcohols and other polyhydroxylated compounds.
• Agrochemical Synthesis: Intermediate in the production of specialized herbicides, fungicides, and plant growth regulators requiring protected diol motifs.
• Material Science Research: Monomer or precursor for developing novel polymers, dendrimers, and functionalized surfaces with specific chemical handles.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and molecular probes for studying biological pathways and interactions.

Basic Information

Product Name	1,3-Ditrityloxypropan-2-Ol
CAS No.	5443-10-7
Molecular Formula	C41H36O3
Molecular Weight	576.73 g/mol
Synonyms	1,3-Bis(trityloxy)-2-propanol; 2-Propanol, 1,3-bis(triphenylmethoxy)-; 1,3-Di-O-tritylglycerol; Glycerol 1,3-ditrityl ether; 1,3-Di(trityloxy)-2-propanol; 1,3-Di-O-trityl-rac-glycerol; DITRITYL GLYCEROL; rac-1,3-Di-O-tritylglycerol
EINECS	226-637-8

Quality Control

Our 1,3-Ditrityloxypropan-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.