Description

1,3:2,5:4,6-Tri-o-Methylene-D-Mannitol CAS NO 5434-31-1 is a high-purity, protected derivative of D-mannitol, a versatile sugar alcohol. This compound is valued for its role as a key chiral intermediate and protecting group in sophisticated organic synthesis. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the production of active ingredients and specialty molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block for synthesizing complex drug candidates, particularly in nucleoside and carbohydrate-based therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Fine Chemical Production: Acts as a starting material or protected intermediate for manufacturing specialty chemicals, flavors, and fragrances.
• Academic & Industrial Research: Employed in chemical research for studying reaction mechanisms, developing new synthetic methodologies, and creating novel molecular architectures.
• Polymer Science: Potential use as a monomer or cross-linking agent in the development of specialty polymers with unique properties.

Basic Information

Product Name	1,3:2,5:4,6-Tri-o-Methylene-D-Mannitol
CAS No.	5434-31-1
Molecular Formula	C9H16O6
Molecular Weight	220.22 g/mol
Synonyms	D-Mannitol 1,3:2,5:4,6-Tri-O-methylene acetal; 1,3:2,5:4,6-Tri-O-methylene-D-mannitol; Tri-O-methylene-D-mannitol; D-Mannitol tri-O-methylene acetal; 2,4:3,5-Di-O-methylene-D-mannitol (alternative numbering); D-Mannitol cyclic trimethylene acetal
EINECS	226-603-7

Quality Control

Our 1,3:2,5:4,6-Tri-o-Methylene-D-Mannitol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Melting Point	Specified range
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.