Description

Ethyl 4-(3-Hydroxyphenyl)-2-Methyl-5-Oxo-4,6,7,8-Tetrahydro-1H-Quinoline-3-Carboxylate is a high-purity, complex heterocyclic compound serving as a critical advanced intermediate in modern organic synthesis. Its unique molecular architecture, featuring a fused quinoline core with a hydroxyphenyl substituent, makes it an invaluable building block for constructing sophisticated pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Used as a scaffold for developing new herbicides, fungicides, or plant growth regulators with enhanced efficacy and selectivity.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the tetrahydroquinoline moiety, a privileged structure in medicinal chemistry.
• Material Science Research: Potential intermediate for creating organic electronic materials or advanced polymers with specific optical or electronic properties.
• Academic & Contract Research: Serves as a standard or starting material for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	Ethyl 4-(3-Hydroxyphenyl)-2-Methyl-5-Oxo-4,6,7,8-Tetrahydro-1H-Quinoline-3-Carboxylate
CAS No.	5405-37-8
Molecular Formula	C19H21NO4
Molecular Weight	327.38 g/mol
Synonyms	Ethyl 4-(3-hydroxyphenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate; 4-(3-Hydroxyphenyl)-2-methyl-5-oxo-4,6,7,8-tetrahydroquinoline-3-carboxylic acid ethyl ester; 5-Oxo-4-(3-hydroxyphenyl)-2-methyl-4,6,7,8-tetrahydroquinoline-3-carboxylic acid ethyl ester; 5405-37-8; 4,6,7,8-Tetrahydro-4-(3-hydroxyphenyl)-2-methyl-5-oxo-1H-quinoline-3-carboxylic acid ethyl ester.
EINECS	Contact for details

Quality Control

Our Ethyl 4-(3-Hydroxyphenyl)-2-Methyl-5-Oxo-4,6,7,8-Tetrahydro-1H-Quinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and reliable documentation supports your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.