Description

2,4,6-Trinitrobenzenesulfonic Acid Sodium Salt is a high-purity, water-soluble derivative of picryl sulfonic acid, valued for its strong electrophilic properties. This compound serves as a critical reagent for the quantitative determination of primary amines and amino groups in peptides, proteins, and other biomolecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require precise and reliable chemical tools for protein analysis and modification.

Application

• Protein & Peptide Analysis: A key reagent for the quantitative determination of primary amino groups via the TNBS (2,4,6-Trinitrobenzenesulfonic acid) assay.
• Bioconjugation Chemistry: Used for the chemical modification and cross-linking of proteins, antibodies, and other biomolecules.
• Pharmaceutical Research: Employed in drug discovery and development for studying protein-ligand interactions and stability.
• Food Science & Nutrition: Applied in the analysis of protein content and lysine availability in food products and feed.
• Polymer & Material Science: Acts as a functionalization agent for introducing reactive groups onto polymer surfaces.
• Diagnostic Kit Manufacturing: Utilized in the production of diagnostic reagents and kits for clinical testing.

Basic Information

Product Name	2,4,6-Trinitrobenzenesulfonic Acid Sodium Salt
CAS No.	5400-70-4
Molecular Formula	C6H2N3NaO9S
Molecular Weight	315.15 g/mol
Synonyms	TNBS Sodium Salt; Picrylsulfonic Acid Sodium Salt; Sodium 2,4,6-Trinitrobenzenesulfonate; 2,4,6-Trinitrobenzene-1-sulfonic Acid Sodium Salt; TNBSA Sodium Salt; Sodium Picrylsulfonate; 1,3,5-Trinitro-2-sulfobenzene Sodium Salt
EINECS	226-456-0

Quality Control

Our 2,4,6-Trinitrobenzenesulfonic Acid Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility (1% in Water)	Clear, yellow solution
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.