Description

2-Iodo-3-Nitro-Benzoic Acid is a halogenated nitrobenzoic acid derivative, a versatile and high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both an iodine substituent and a nitro group on the aromatic ring, makes it a critical building block for constructing complex molecules with specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting specific receptors or requiring halogen bonding interactions.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators where the iodine atom can be leveraged for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and dyes, where its substituents influence molecular packing and optoelectronic properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine atom.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems and mechanisms.

Basic Information

Product Name	2-Iodo-3-Nitro-Benzoic Acid
CAS No.	5398-69-6
Molecular Formula	C7H4INO4
Molecular Weight	293.02 g/mol
Synonyms	3-Nitro-2-iodobenzoic acid; 2-Iodo-3-nitrobenzoic acid; Benzoic acid, 2-iodo-3-nitro-; 2-Iodo-3-nitro-benzoic acid; 3-Nitro-2-iodo-benzoic acid; 2-Iodo-3-nitrobenzoic acid; 5398-69-6 (CAS)
EINECS	Contact for details

Quality Control

We supply 2-Iodo-3-Nitro-Benzoic Acid in high-purity grades suitable for research and commercial synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. We adhere to a robust quality management system to guarantee batch-to-batch consistency and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.