Description

1-Benzothiophene-3-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel pharmaceuticals and functional materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its conjugated benzothiophene core.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and the creation of novel chemical entities.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and organic pigments.

Basic Information

Product Name	1-Benzothiophene-3-Carboxylic Acid
CAS No.	5381-25-9
Molecular Formula	C9H6O2S
Molecular Weight	178.21 g/mol
Synonyms	Benzothiophene-3-carboxylic acid; 3-Benzothienylcarboxylic acid; 1-Benzothiophene-3-carboxylic acid; 3-Carboxybenzothiophene; 3-Benzothiophenecarboxylic acid; Benzo[b]thiophene-3-carboxylic acid; 1-Thianaphthene-3-carboxylic acid; 5381-25-9 (CAS)
EINECS	226-357-5

Quality Control

Our 1-Benzothiophene-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.