Description

1-Benzyloxy-3-Iodopropane is a versatile alkylating agent and a valuable building block in organic synthesis. This compound is particularly significant for introducing the benzyl-protected hydroxypropyl moiety into target molecules, enabling the construction of complex chemical architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications ranging from API intermediate synthesis to ligand preparation.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing side chains or linker segments.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring specific ether-linked propyl chains.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine or nitrogen-based ligands used in homogeneous catalysis.
• Material Science Monomer: Can be utilized to create functionalized polymers or dendrimers with tailored properties.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in various palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki).
• Protecting Group Chemistry: The benzyloxy group can serve as a protecting group for alcohols in multi-step synthetic sequences.
• Chemical Research & Development: A fundamental tool in academic and industrial R&D labs for exploring new synthetic methodologies.

Basic Information

Product Name	1-Benzyloxy-3-Iodopropane
CAS No.	5375-00-8
Molecular Formula	C10H13IO
Molecular Weight	276.11 g/mol
Synonyms	3-Iodopropyl Benzyl Ether; Benzyl 3-Iodopropyl Ether; (3-Iodopropoxy)methyl]benzene; 1-Iodo-3-(benzyloxy)propane; NSC 401122; Benzyloxypropyl Iodide; ω-Iodopropyl Benzyl Ether
EINECS	226-355-6

Quality Control

Our 1-Benzyloxy-3-Iodopropane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Specific Gravity (20°C)	1.45 - 1.55
Refractive Index (n20D)	1.550 - 1.560

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.