Description

3-(4-Oxo-3,4-Dihydro-Quinazolin-2-Yl)-Propionic Acid CAS NO 5368-37-6 is a high-purity, specialized organic compound belonging to the quinazolinone class, serving as a critical building block in advanced chemical synthesis. Its unique molecular structure makes it an invaluable intermediate for research and development in the pharmaceutical and agrochemical sectors. This product is essential for medicinal chemists and process development scientists focused on creating novel active ingredients and fine chemicals.

Application

This versatile quinazolinone derivative is a key intermediate in several high-value industrial and research applications:

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of potential drug candidates, particularly in oncology and neurology research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the quinazolinone moiety into target molecules.
• Biochemical Research: Acts as a precursor for enzyme inhibitors and probes used in biochemical and pharmacological studies.
• Material Science: Investigated for the development of specialty polymers and organic electronic materials.

Basic Information

Product Name	3-(4-Oxo-3,4-Dihydro-Quinazolin-2-Yl)-Propionic Acid
CAS No.	5368-37-6
Molecular Formula	C₁₁H₁₀N₂O₃
Molecular Weight	218.21 g/mol
Synonyms	2-(2-Carboxyethyl)-4(3H)-quinazolinone; 3-(4-Oxo-3,4-dihydro-2-quinazolinyl)propanoic acid; 4(3H)-Quinazolinone, 2-(2-carboxyethyl)-; 3-(4-Oxo-3,4-dihydroquinazolin-2-yl)propionic acid; Quinazolin-2-yl-propionic acid; 2-(3-Carboxypropyl)-4-hydroxyquinazoline; 5368-37-6 (CAS Registry)
EINECS	Contact for details

Quality Control

Our production of 3-(4-Oxo-3,4-Dihydro-Quinazolin-2-Yl)-Propionic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.