Description

3-Chloro-2,4,5,6-Tetrafluorobenzoic Acid is a high-value, multi-fluorinated benzoic acid derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both chlorine and fluorine substituents, makes it an essential precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams and production chemists in the pharmaceutical, agrochemical, and specialty materials industries for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorine-containing liquid crystal compounds used in high-performance displays.
• Polymer Modification: Employed to introduce fluorinated benzoate groups into polymers, improving their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterifications, and amide formations to create complex fluorinated aromatic structures for material science research.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and creating compound libraries for screening in various industries.

Basic Information

Product Name	3-Chloro-2,4,5,6-Tetrafluorobenzoic Acid
CAS No.	5360-81-6
Molecular Formula	C7HClF4O2
Molecular Weight	228.53 g/mol
Synonyms	2,4,5,6-Tetrafluoro-3-chlorobenzoic Acid; Benzoic acid, 3-chloro-2,4,5,6-tetrafluoro-; 3-Chlorotetrafluorobenzoic Acid; 3-Chloro-2,4,5,6-tetrafluorobenzoic acid; 5360-81-6; TCFBA (abbrev.)
EINECS	226-342-9

Quality Control

Every batch of 3-Chloro-2,4,5,6-Tetrafluorobenzoic Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards and provide full traceability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, guaranteeing consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.