Description

Methyl 7-Chloro-4-Hydroxyquinoline-2-Carboxylate is a high-purity, versatile quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is essential for research and development in the pharmaceutical sector, particularly for creating novel active pharmaceutical ingredients (APIs) and complex heterocyclic molecules. It is primarily sought after by fine chemical manufacturers, pharmaceutical R&D laboratories, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of antimalarial and antibacterial drug candidates, leveraging the bioactive quinoline scaffold.
• Medicinal Chemistry Research: A versatile building block for constructing complex molecular libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Used in the multi-step synthesis of specialty chemicals, agrochemicals, and other functionalized quinoline derivatives.
• Organic Light-Emitting Diode (OLED) Materials: Potential intermediate in the development of electron-transport or emissive layer materials due to the quinoline structure's electronic properties.
• Coordination Chemistry: Can act as a ligand or precursor for metal-organic frameworks (MOFs) and catalytic complexes.

Basic Information

Product Name	Methyl 7-Chloro-4-Hydroxyquinoline-2-Carboxylate
CAS No.	5347-19-3
Molecular Formula	C11H8ClNO3
Molecular Weight	237.64 g/mol
Synonyms	7-Chloro-4-hydroxyquinoline-2-carboxylic acid methyl ester; Methyl 7-chloro-4-oxo-1,4-dihydroquinoline-2-carboxylate; 2-Quinolinecarboxylic acid, 7-chloro-1,4-dihydro-4-oxo-, methyl ester; 7-Chloro-4-hydroxy-2-quinolinecarboxylic acid methyl ester; 4-Hydroxy-7-chloroquinoline-2-carboxylic acid methyl ester
EINECS	226-297-9

Quality Control

Our Methyl 7-Chloro-4-Hydroxyquinoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.