Description

4-Bromo-3-Nitroanisole is a versatile halogenated nitroaromatic ether, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive bromine and nitro group on a methoxybenzene scaffold, enabling precise functionalization for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted anisole core.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Dye and Pigment Manufacturing: Serves as a precursor for the development of complex organic dyes and colorants.
• Material Science Research: Employed in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Nucleophilic Aromatic Substitution: The activated nitro group facilitates substitution reactions for further chemical diversification.

Basic Information

Item	Detail
Product Name	4-Bromo-3-Nitroanisole
CAS No.	5344-78-5
Molecular Formula	C7H6BrNO3
Molecular Weight	232.03 g/mol
Synonyms	1-Bromo-4-methoxy-2-nitrobenzene; 3-Nitro-4-bromoanisole; 4-Bromo-3-nitro-1-methoxybenzene; 2-Nitro-4-bromoanisole; 4-Bromo-3-nitroanisole; Anisole, 4-bromo-3-nitro-; 4-Methoxy-2-nitro-1-bromobenzene; Benzene, 1-bromo-4-methoxy-2-nitro-
EINECS	226-291-1

Quality Control

Our 4-Bromo-3-Nitroanisole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.