Description

n-Formyl-Dl-Leucine is a chemically modified derivative of the amino acid leucine, featuring a formyl protecting group on the amine functionality. This modification is critical in peptide synthesis and organic chemistry, where it serves as a versatile intermediate to control reactivity and prevent unwanted side reactions. It is primarily utilized by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in the production of bioactive peptides, custom amino acid derivatives, and advanced organic compounds.

Application

• Peptide Synthesis Intermediate: Used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Research: Serves as a key precursor in the development and study of novel peptide-based drugs and therapeutic agents.
• Biochemical Research: Employed in studies of amino acid metabolism, enzyme substrates, and protein engineering.
• Fine Chemical Production: Acts as a chiral synthon for the manufacture of complex organic molecules and specialty chemicals.
• Protecting Group Chemistry: Utilized in methodologies where selective protection and deprotection of amino groups are required.

Basic Information

Product Name	n-Formyl-Dl-Leucine
CAS No.	5338-45-4
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	DL-Leucine, N-formyl-; Formylleucine; N-Formylleucine; (±)-N-Formylleucine; 2-Formamido-4-methylpentanoic acid; NSC 3348; Leucine, N-formyl-, DL-; F-Leu-OH
EINECS	226-257-7

Quality Control

Our n-Formyl-Dl-Leucine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, chiral purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (DL Ratio)	~ 1:1 (Racemic mixture)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.