Description

4-(Phenylmethoxycarbonylamino)Benzoic Acid is a protected amino acid derivative, specifically a benzyloxycarbonyl (Cbz or Z)-protected para-aminobenzoic acid. This compound is a crucial pharmaceutical intermediate and building block in organic synthesis, valued for its role in peptide coupling and the controlled introduction of functional groups. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis.
• Organic Synthesis: Used as a versatile precursor for introducing the 4-aminobenzoic acid moiety into target molecules under controlled conditions.
• Linker Molecule: Employed in bioconjugation and the development of prodrugs due to its carboxylic acid and protected amine functionalities.
• Chemical Research: A valuable reagent in academic and industrial laboratories for methodological development and novel compound library generation.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers and functional materials.

Basic Information

Product Name	4-(Phenylmethoxycarbonylamino)Benzoic Acid
CAS No.	5330-71-2
Molecular Formula	C15H13NO4
Molecular Weight	271.27 g/mol
Synonyms	4-[(Benzyloxycarbonyl)amino]benzoic acid; N-Cbz-4-aminobenzoic acid; N-Carbobenzoxy-4-aminobenzoic acid; 4-(N-Carbobenzyloxy)aminobenzoic acid; 4-(Benzyloxycarbonylamino)benzoic acid; p-(Carbobenzyloxyamino)benzoic acid; Z-4-Abz-OH; Benzoic acid, 4-[[(phenylmethoxy)carbonyl]amino]-
EINECS	226-223-8

Quality Control

Our 4-(Phenylmethoxycarbonylamino)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key specifications such as assay and impurity profiles. Our quality commitment supports applications in GMP-oriented synthesis and critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.