Description

2-Bromo-N-(2-nitrophenyl)acetamide is a specialized brominated aromatic amide building block of significant interest in synthetic organic chemistry. Its molecular structure, featuring both a reactive bromoacetamide group and a nitro-substituted aromatic ring, makes it a versatile intermediate for constructing more complex nitrogen-containing heterocycles and functionalized molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those containing indole, quinazoline, or other fused heterocyclic scaffolds with potential biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the nitro and bromo functionalities allow for further derivatization.
• Organic Synthesis Building Block: Serves as a versatile electrophile in nucleophilic substitution reactions (e.g., with amines, thiols) and in cyclization reactions to form lactams and other heterocycles.
• Material Science Research: Employed in the creation of specialty polymers and functional organic materials that require nitro-aromatic or bromoacetamide motifs for specific electronic or binding properties.
• Chemical Biology Probe Development: Useful for synthesizing activity-based probes or affinity labels that target specific enzymes or proteins in biochemical studies.

Basic Information

Product Name	2-Bromo-N-(2-nitrophenyl)acetamide
CAS No.	5326-94-3
Molecular Formula	C8H7BrN2O3
Molecular Weight	259.06 g/mol
Synonyms	N-(2-Nitrophenyl)-2-bromoacetamide; 2-Bromoacet-2'-nitroanilide; 2-Bromo-N-(2-nitrobenzene)acetamide; α-Bromo-2'-nitroacetanilide; Acetamide, 2-bromo-N-(2-nitrophenyl)-; 2-Bromo-2'-nitroacetanilide; Bromo(nitroanilino)ethanone; 2-Bromoacetylamino-2-nitrobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-N-(2-nitrophenyl)acetamide is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our standard material typically meets a purity specification of ≥97% (by HPLC), with comprehensive identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and physical characteristics. We support custom synthesis and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.