Description

4-Iodo-3-Nitrotoluene is a halogenated nitroaromatic compound that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both iodine and nitro substituents on a toluene backbone, makes it a critical building block for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) and specialty dyes. This high-purity intermediate is essential for research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the iodine and nitro functional groups are integral to biological activity.
• Dye and Pigment Manufacturing: Serves as a building block for synthesizing specialized azo dyes and other colorants with specific light-fastness and hue properties.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers that incorporate halogenated aromatic units.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to the reactive iodine substituent.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name	4-Iodo-3-Nitrotoluene
CAS No.	5326-39-6
Molecular Formula	C7H6INO2
Molecular Weight	263.03 g/mol
Synonyms	1-Iodo-2-methyl-5-nitrobenzene; 3-Nitro-4-iodotoluene; 4-Iodo-3-nitrotoluene; 2-Methyl-5-nitro-1-iodobenzene; Toluene, 4-iodo-3-nitro-; 5-Nitro-2-iodotoluene; 4-Iodo-3-methylnitrobenzene
EINECS	226-185-6

Quality Control

Our 4-Iodo-3-Nitrotoluene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.