Description

Diethyl 2-Bromoethylphosphonate is a versatile organophosphorus compound widely used as a key synthetic intermediate. Its primary value lies in its role as a Horner-Wadsworth-Emmons (HWE) reagent, enabling the efficient construction of carbon-carbon double bonds, particularly in the synthesis of α,β-unsaturated esters and other valuable olefins. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it facilitates the production of complex molecules and active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those containing vinyl or acrylate moieties.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that require specific olefinic structures.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent precursor for creating specialized polymers and functional materials.
• Organic Synthesis & Research: A fundamental reagent in academic and industrial R&D laboratories for constructing complex organic molecules via the Horner-Wadsworth-Emmons olefination reaction.
• Ligand & Catalyst Preparation: Employed in the synthesis of phosphonate-based ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Flavor & Fragrance Industry: Used in the synthetic pathways for certain aroma chemicals and flavor compounds.

Basic Information

Product Name	Diethyl 2-Bromoethylphosphonate
CAS No.	5324-30-1
Molecular Formula	C6H14BrO3P
Molecular Weight	245.05 g/mol
Synonyms	(2-Bromoethyl)phosphonic Acid Diethyl Ester; Diethyl (2-Bromoethyl)phosphonate; 2-Bromoethylphosphonic Acid Diethyl Ester; Ethyl 2-Bromoethylphosphonate; NSC 404058; Diethyl Phosphorobromoethylate; Bromoethylphosphonic Acid Diethyl Ester
EINECS	226-185-9

Quality Control

Our Diethyl 2-Bromoethylphosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.460 - 1.470
Density (g/mL, 20°C)	1.35 - 1.45

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.