Description

1-Hydroxypyrene is a high-purity polycyclic aromatic hydrocarbon (PAH) derivative, serving as a critical intermediate and reference standard in advanced chemical synthesis and analytical research. Its significance lies in its role as a key metabolite and biomarker for monitoring human exposure to pyrene and other PAHs, which are important environmental contaminants. This compound is essential for researchers and manufacturers in the environmental monitoring, analytical chemistry, pharmaceutical development, and material science sectors who require precise and reliable chemical building blocks.

Application

• Biomarker and Metabolite Studies: Used as a primary analytical standard for the quantification of 1-hydroxypyrene in biological samples (e.g., urine) to assess human exposure to pyrene and other polycyclic aromatic hydrocarbons (PAHs).
• Environmental Analysis: Serves as a crucial reference material in environmental testing laboratories for monitoring PAH contamination in soil, water, and air particulates.
• Chemical Synthesis Intermediate: Acts as a versatile building block for the synthesis of more complex PAH derivatives, fluorescent probes, and specialized organic compounds.
• Toxicological Research: Employed in studies investigating the metabolism, genotoxicity, and carcinogenic potential of PAHs.
• Analytical Method Development: Utilized for calibrating instruments and validating analytical methods such as HPLC, GC-MS, and fluorescence spectroscopy.
• Material Science Research: Investigated for potential applications in the development of organic semiconductors, luminescent materials, and sensors due to its aromatic structure.

Basic Information

Product Name	1-Hydroxypyrene
CAS No.	5315-79-7
Molecular Formula	C₁₆H₁₀O
Molecular Weight	218.25 g/mol
Synonyms	1-Pyrenol; 1-Pyrenyl alcohol; 1-Hydroxypyrene; Pyren-1-ol; 1-Pyreneol; Hydroxypyrene; 1-HP; 1-OH-Pyrene
EINECS	226-158-7

Quality Control

Our 1-Hydroxypyrene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive analytical and research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity confirmation, and impurity profiles. While specific pharmacopeial monographs (e.g., USP, EP) may not be established for this research chemical, our quality system adheres to ISO 9001 principles, and material can be supplied to meet custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) as indicated in its chemical properties. For long-term storage, consider storing under an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	181 - 185 °C
Loss on Drying	≤ 0.5 %
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.