Description

8-Fluoro-2-Methyl-4-Quinolinol is a fluorinated quinoline derivative, a versatile heterocyclic building block prized for its unique structural and electronic properties. This compound is critical for researchers and manufacturers developing advanced materials and active pharmaceutical ingredients (APIs). It serves as a key intermediate for the synthesis of complex molecules in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced electronic materials due to its fluorinated aromatic structure.
• Coordination Chemistry: Acts as a chelating ligand for metal ions in catalytic systems and in the preparation of metal-organic frameworks (MOFs).
• Dye & Pigment Synthesis: Utilized as an intermediate for creating specialized fluorinated dyes and pigments with enhanced properties.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial R&D labs.

Basic Information

Product Name	8-Fluoro-2-Methyl-4-Quinolinol
CAS No.	5288-22-2
Molecular Formula	C10H8FNO
Molecular Weight	177.18 g/mol
Synonyms	8-Fluoro-2-methylquinolin-4-ol; 8-Fluoro-2-methyl-4-hydroxyquinoline; 4-Hydroxy-8-fluoro-2-methylquinoline; 2-Methyl-8-fluoro-4-quinolinol; 8-Fluoro-2-methyl-4(1H)-quinolinone (tautomer); 5288-22-2; FC-0423
EINECS	Contact for details

Quality Control

Our 8-Fluoro-2-Methyl-4-Quinolinol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.