Description

(1R,4S)-4,7,7-Trimethylbicyclo[4.1.0]hept-2-ene is a high-purity, chiral bicyclic monoterpene derivative with a strained, functionalized structure. This compound serves as a valuable and versatile chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is particularly critical for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for the development of active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in terpene-based therapeutics.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for high-value flavors, fragrances, and specialty chemicals requiring specific stereochemistry.
• Organic Synthesis Research: An essential reagent in academic and industrial R&D for studying cyclopropanation reactions and strain-release chemistry.
• Material Science: Potential monomer or modifier for creating polymers with unique thermal or mechanical properties derived from its rigid bicyclic framework.
• Catalyst & Ligand Development: Used as a scaffold for developing novel chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Item	Details
Product Name	(1R,4S)-4,7,7-Trimethylbicyclo[4.1.0]hept-2-ene
CAS No.	5208-50-4
Molecular Formula	C10H16
Molecular Weight	136.23 g/mol
Synonyms	(-)-3-Carene; (1R,4S)-(-)-3-Carene; L-3-Carene; (1R,4S)-3-Carene; 3-Carene, (-)-; 4,7,7-Trimethyl-3-norcarene; Bicyclo[4.1.0]hept-2-ene, 4,7,7-trimethyl-, (1R,4S)-; (1R,4S)-4,7,7-Trimethylbicyclo[4.1.0]hept-2-ene
EINECS	Contact for details

Quality Control

Every batch of our (1R,4S)-4,7,7-Trimethylbicyclo[4.1.0]hept-2-ene is produced and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure reliable purity and enantiomeric excess (e.e.) for your critical synthesis workflows. Certificates of Analysis (COA) detailing identity, purity by GC/HPLC, chiral purity, and specific tests are available upon request and with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C to minimize volatility and oxidation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (e.e.)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.