Description

2-[2-[2-(2-Chloroethoxy)Ethoxy]Ethoxy]Ethanol is a versatile chlorinated polyethylene glycol derivative, serving as a crucial reactive intermediate in advanced organic synthesis. Its unique structure, featuring a terminal hydroxyl group and a chloroethyl chain, makes it an essential building block for creating functionalized polymers and specialty surfactants. This compound is particularly valuable for industries requiring custom-tailored chemical functionality, such as pharmaceutical development, polymer science, and materials engineering.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs, drug conjugates, and active pharmaceutical ingredients (APIs) requiring polyethylene glycol (PEG) linkers for enhanced solubility or targeted delivery.
• Polymer & Resin Modification: Acts as a reactive monomer or chain extender for producing specialty polyethers, polyurethanes, and epoxy resins with tailored properties.
• Surfactant & Emulsifier Synthesis: Serves as a key precursor for manufacturing non-ionic surfactants and emulsifiers used in agrochemicals, coatings, and personal care formulations.
• Crosslinking Agent: Employed in the production of crosslinked hydrogels, networks, and elastomers for biomedical and industrial applications.
• Chemical Functionalization: Utilized to introduce hydrophilic PEG spacers and reactive sites onto surfaces, nanoparticles, or biomolecules in materials science and bioconjugation.
• Lubricant & Plasticizer Additive: Incorporated as a functional additive to modify the viscosity, stability, or compatibility of industrial lubricants and plasticizers.

Basic Information

Product Name	2-[2-[2-(2-Chloroethoxy)Ethoxy]Ethoxy]Ethanol
CAS No.	5197-66-0
Molecular Formula	C8H17ClO4
Molecular Weight	212.67 g/mol
Synonyms	2-(2-(2-(2-Chloroethoxy)ethoxy)ethoxy)ethanol; Tetraethylene Glycol Monochlorohydrin; 2-Chloroethoxy-tetraethylene glycol; 1-Chloro-3,6,9,12-tetraoxatetradecan-14-ol; Chlorinated Tetraethylene Glycol; 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol (alternate punctuation); PEG4 Chlorohydrin; 3,6,9,12-Tetraoxa-1-chlorotetradecan-14-ol
EINECS	Contact for details

Quality Control

Our 2-[2-[2-(2-Chloroethoxy)Ethoxy]Ethoxy]Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay, identity confirmation, and impurity profiling, to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing specific results are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.455 - 1.465
Density (g/mL, 20°C)	1.10 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.