Description

2-Bromo-4-Nitroanisole is a versatile brominated aromatic compound that serves as a critical building block in advanced organic synthesis. Its value lies in providing a reactive halogen and nitro-substituted aromatic core, enabling precise molecular construction for high-value intermediates. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the bromo and nitro functional groups are integral to biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing azo dyes and other colored compounds, contributing to chromophore development.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and polymers that require specific halogenated aromatic units.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig amination, facilitating carbon-carbon and carbon-heteroatom bond formation.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and constructing novel chemical libraries in academic and industrial R&D settings.

Basic Information

Product Name	2-Bromo-4-Nitroanisole
CAS No.	5197-28-4
Molecular Formula	C7H6BrNO3
Molecular Weight	232.03 g/mol
Synonyms	1-Bromo-2-methoxy-5-nitrobenzene; 2-Bromo-4-nitro-1-methoxybenzene; 4-Nitro-2-bromoanisole; 5-Nitro-2-bromoanisole; Anisole, 2-bromo-4-nitro-; Benzene, 1-bromo-2-methoxy-5-nitro-; NSC 403791
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Nitroanisole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, GC, NMR, and other relevant techniques. Our quality commitment ensures the material meets the stringent requirements for use in regulated synthesis and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.