Description

2,6-Dichloro-4-Phenyl-Quinazoline is a versatile and high-value heterocyclic building block, primarily recognized for its role as a key intermediate in advanced organic synthesis. Its molecular structure makes it a critical precursor for the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing quinazoline-based drug candidates, including kinase inhibitors and anticancer agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized quinazoline-derived dyes and pigments.
• Academic & R&D: A valuable reagent for medicinal chemistry research and the exploration of new heterocyclic compounds in university and corporate laboratories.
• Custom Synthesis: Used by fine chemical manufacturers for contract synthesis and the production of complex, customer-specific molecules.

Basic Information

Product Name	2,6-Dichloro-4-Phenyl-Quinazoline
CAS No.	5185-54-6
Molecular Formula	C14H8Cl2N2
Molecular Weight	275.13 g/mol
Synonyms	4-Phenyl-2,6-dichloroquinazoline; 2,6-Dichloro-4-phenylquinazoline; Quinazoline, 2,6-dichloro-4-phenyl-; 2,6-Dichloro-4-phenyl-1,3-diazanaphthalene; NSC 403697; 2,6-Dichloro-4-phenyl-benzo[d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-4-Phenyl-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.