Description

4-Bromophenyl 4-Methylphenyl Sulfone is a high-purity diaryl sulfone derivative, a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and methyl substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications ranging from catalyst ligands to polymer precursors.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring sulfone or aryl halide functional groups.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfone moiety contributes to biological activity.
• Ligand Precursor in Catalysis: Serves as a starting material for the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands used in cross-coupling and other metal-catalyzed reactions.
• Polymer & Material Science: Acts as a monomer or comonomer in the production of high-performance engineering plastics, such as polysulfones, which offer excellent thermal and chemical resistance.
• Organic Electronic Materials: Investigated as a core component in the development of organic semiconductors, OLEDs, and photovoltaic materials due to its electron-withdrawing sulfone group.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	4-Bromophenyl 4-Methylphenyl Sulfone
CAS No.	5184-70-3
Molecular Formula	C13H11BrO2S
Molecular Weight	311.19 g/mol
Synonyms	1-Bromo-4-[(4-methylphenyl)sulfonyl]benzene; 4-Bromophenyl p-Tolyl Sulfone; p-Bromophenyl p-Tolyl Sulfone; (4-Bromophenyl)(4-methylphenyl)sulfone; 4-Methylphenyl 4-bromophenyl sulfone; NSC 403107; Bis(4-bromophenyl) sulfone analog
EINECS	Contact for details

Quality Control

Every batch of our 4-Bromophenyl 4-Methylphenyl Sulfone is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure consistency and purity. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, GC, NMR, and other relevant techniques to verify identity, potency, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.