Description

1-Methyladenine is a modified nucleobase derivative of adenine, a fundamental building block in biochemistry. This compound is a crucial intermediate and research chemical in the synthesis of modified nucleotides and nucleosides, which are essential for studying cellular processes and developing novel therapeutics. It serves the needs of pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on nucleic acid chemistry, epigenetics, and drug discovery.

Application

• Pharmaceutical Research & Development: As a key synthetic intermediate in the creation of nucleoside analogs for antiviral and anticancer drug candidates.
• Biochemical Research: Used in studies of enzyme mechanisms, particularly methyltransferases involved in epigenetic regulation.
• Nucleic Acid Chemistry: Serves as a building block for the synthesis of oligonucleotides with specific modifications for diagnostic probes or therapeutic aptamers.
• Reference Standard: Employed as an analytical standard in HPLC or LC-MS for the quantification of methylated adenine derivatives in biological samples.
• Enzyme Substrate Studies: Utilized to investigate the activity and specificity of various adenosine-processing enzymes.

Basic Information

Product Name	1-Methyladenine
CAS No.	5142-22-3
Molecular Formula	C6H7N5
Molecular Weight	149.15 g/mol
Synonyms	N1-Methyladenine; 6-Amino-1-methylpurine; 1-Methyl-6-aminopurine; 1-MA; Adenine, 1-methyl-; 1-Methyl-9H-purin-6-amine
EINECS	225-904-9

Quality Control

Our 1-Methyladenine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.