Description

4-Hydroxy-1-Methylbicyclo[2.2.2]Octan-2-One is a specialized bicyclic organic compound that serves as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique, rigid molecular framework is critical for constructing complex molecules with precise stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in projects requiring stereochemical control.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to create enantiomerically pure compounds for high-value applications.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization due to its constrained, three-dimensional structure.
• Fine Chemical Production: Serves as a precursor in the synthesis of specialty chemicals, fragrances, and advanced materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry within university and corporate laboratories.

Basic Information

Product Name	4-Hydroxy-1-Methylbicyclo[2.2.2]Octan-2-One
CAS No.	5122-77-0
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	1-Methyl-4-hydroxybicyclo[2.2.2]octan-2-one; 4-Hydroxy-1-methyl-2-bicyclo[2.2.2]octanone; 1-Methylbicyclo[2.2.2]octane-2-one, 4-hydroxy-; Bicyclo[2.2.2]octan-2-one, 4-hydroxy-1-methyl-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chemical intermediates. Production batches are analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.