Description

4-Chloro-1,2,5-thiadiazole-3-carboxylic acid is a high-value heterocyclic building block characterized by its reactive carboxylic acid and chloro-substituted thiadiazole core. This compound matters as a versatile synthon for constructing complex molecules in advanced research and development, offering a unique combination of electrophilic and nucleophilic sites for selective derivatization. It is primarily needed by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, crop protection, and the synthesis of functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Building Block: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, heteroaromatic structure.
• Chemical Research & Development: Serves as a fundamental scaffold in medicinal and synthetic chemistry for exploring new chemical spaces and reaction pathways.
• Ligand and Catalyst Design: Utilized to construct complex chelating ligands for metal catalysis and coordination chemistry applications.

Basic Information

Product Name	4-Chloro-1,2,5-thiadiazole-3-carboxylic Acid
CAS No.	5097-44-9
Molecular Formula	C3HClN2O2S
Molecular Weight	164.57 g/mol
Synonyms	4-Chloro-1,2,5-thiadiazole-3-carboxylic acid; 3-Carboxy-4-chloro-1,2,5-thiadiazole; 4-Chloro-1,2,5-thiadiazole-3-carboxylic acid; 4-Chloro-1,2,5-thiadiazole-3-carboxylic acid; 4-Chloro-1,2,5-thiadiazole-3-carboxylic acid; 4-Chloro-1,2,5-thiadiazole-3-carboxylic acid; 4-Chloro-1,2,5-thiadiazole-3-carboxylic acid; 4-Chloro-1,2,5-thiadiazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-1,2,5-thiadiazole-3-carboxylic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency meet the highest standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.