Description

3-Phenyl-1H-Pyrazole-5-Carboxylic Acid is a heterocyclic carboxylic acid derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its core value lies in its bifunctional pyrazole-carboxylic acid structure, which is critical for constructing complex molecules with targeted biological or material properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-purity building block for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting inflammation, metabolic disorders, and central nervous system (CNS) diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators, leveraging the pyrazole core's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and functional polymers due to its rigid, aromatic structure.
• Chemical Biology & Proteomics: Utilized as a scaffold or linker in the design of chemical probes and activity-based probes for studying enzyme function and protein interactions.

Basic Information

Product Name	3-Phenyl-1H-Pyrazole-5-Carboxylic Acid
CAS No.	5071-61-4
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	5-Pyrazolecarboxylic acid, 3-phenyl-; 3-Phenyl-1H-pyrazole-5-carboxylic acid; 1H-Pyrazole-5-carboxylic acid, 3-phenyl-; 3-Phenylpyrazole-5-carboxylic acid; 5-Carboxy-3-phenylpyrazole; 3-Phenyl-5-pyrazolecarboxylic acid; 3-Phenyl-1H-1,2-diazole-5-carboxylic acid; 5-Carboxy-1H-3-phenylpyrazole
EINECS	Contact for details

Quality Control

Our 3-Phenyl-1H-Pyrazole-5-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting cGMP principles for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.