Description

4(3H)-Quinazolinone, 8-Hydroxy-2-Methyl-3-(2-Methylphenyl)- is a specialized quinazolinone derivative, a heterocyclic compound of significant interest in advanced organic synthesis. This compound serves as a critical pharmacological intermediate and a versatile building block for the development of novel active molecules. It is primarily required by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) in academic and industrial labs.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic systems due to its reactive quinazolinone core and functional groups.
• Agrochemical Research: Investigated as an intermediate for developing novel crop protection agents and pesticides.
• Biochemical Tool Compound: Potential use in biochemical assays and as a probe for studying enzyme interactions or biological pathways.

Basic Information

Product Name	4(3H)-Quinazolinone, 8-Hydroxy-2-Methyl-3-(2-Methylphenyl)-
CAS No.	5060-53-7
Molecular Formula	C₁₆H₁₄N₂O₂
Molecular Weight	266.30 g/mol
Synonyms	8-Hydroxy-2-methyl-3-(o-tolyl)quinazolin-4(3H)-one; 3-(2-Methylphenyl)-8-hydroxy-2-methyl-4(3H)-quinazolinone; 2-Methyl-8-hydroxy-3-(2-methylphenyl)-4(3H)-quinazolinone; 8-Hydroxy-2-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone; 3-(o-Tolyl)-8-hydroxy-2-methylquinazolin-4(3H)-one; Quinazolin-4(3H)-one, 8-hydroxy-2-methyl-3-(2-methylphenyl)-; 5060-53-7 (CAS Index Name).
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone derivative is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.