Description

6-Hydroxy-2-Methyl-3-(2-Methylphenyl)Quinazolin-4(3H)-One is a high-purity, synthetically derived quinazolinone derivative, a versatile heterocyclic scaffold of significant commercial interest. This compound serves as a critical pharmaceutical intermediate and a valuable building block in advanced organic synthesis for research and development. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used as a core structure for developing new pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Organic Synthesis Building Block: Employed in constructing complex heterocyclic compounds for material science and chemical research due to its reactive quinazolinone core.
• Biochemical Research: Acts as a reference standard or a probe molecule in enzymatic and receptor-binding studies.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing specialized quinazolinone-based colorants and fluorescent markers.

Basic Information

Product Name	6-Hydroxy-2-Methyl-3-(2-Methylphenyl)Quinazolin-4(3H)-One
CAS No.	5060-51-5
Molecular Formula	C₁₆H₁₄N₂O₂
Molecular Weight	266.30 g/mol
Synonyms	3-(2-Methylphenyl)-6-hydroxy-2-methyl-4(3H)-quinazolinone; 6-Hydroxy-2-methyl-3-(o-tolyl)quinazolin-4(3H)-one; 2-Methyl-6-hydroxy-3-(2-methylphenyl)-4(3H)-quinazolinone; NSC 403169; Quinazolin-4(3H)-one, 6-hydroxy-2-methyl-3-(2-methylphenyl)-; 6-Hydroxy-2-methyl-3-(2-methylphenyl)-4-quinazolinone
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-2-Methyl-3-(2-Methylphenyl)Quinazolin-4(3H)-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.