Description

Trimethylsulfoxonium Chloride is a versatile sulfoxonium ylide reagent with significant synthetic utility. It serves as a key methylene transfer agent, enabling the efficient synthesis of epoxides from carbonyl compounds under mild conditions. This makes it an indispensable intermediate for pharmaceutical research, agrochemical development, and advanced material science, where precise molecular construction is critical.

Application

• Pharmaceutical Intermediate: Core reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing epoxide rings and other strained heterocycles.
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and fungicides as a building block for complex molecular architectures.
• Organic Synthesis & Research: A fundamental methylene transfer agent for the Corey-Chaykovsky reaction, converting ketones and aldehydes to epoxides, and for generating sulfur ylides.
• Material Science: Employed in the research and development of specialty polymers and functional materials requiring specific sulfur-containing motifs.
• Chemical Catalysis: Acts as a precursor or co-reagent in various catalytic cycles and transition metal-mediated transformations.

Basic Information

Product Name	Trimethylsulfoxonium Chloride
CAS No.	5034-06-0
Molecular Formula	C₃H₉ClOS
Molecular Weight	128.62 g/mol
Synonyms	Trimethylsulfoxonium chloride; Sulfoxonium, trimethyl-, chloride; Trimethyloxosulfonium chloride; NSC 163044; Trimethyl sulfoxonium chloride; (Trimethyl-λ⁴-sulfanylidene)oxonium chloride
EINECS	225-719-4

Quality Control

Our Trimethylsulfoxonium Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay (by titration), identification (IR), and impurity profiling, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing purity, physical characteristics, and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (Titration)	≥ 98.0 %
Water Content (KF)	≤ 1.0 %
Melting Point	~210°C (dec.)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.