Description

Diethyl Chlorophosphite is a versatile organophosphorus reagent primarily used as a key intermediate in organic synthesis. Its high reactivity makes it invaluable for constructing phosphorus-containing compounds and for use as a chlorinating agent. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of phosphate prodrugs, nucleotide analogs, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of organophosphate insecticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for phosphite and phosphonite ligands used in asymmetric catalysis and transition metal complexes.
• Flame Retardant Production: An intermediate in the manufacture of phosphorus-based flame retardants for polymers and textiles.
• Chemical Research & Development: Employed in laboratories for the phosphorylation of alcohols and phenols, and in the preparation of other organophosphorus derivatives.
• Polymer Modification: Used to introduce phosphorus groups into polymer chains to alter material properties such as flame resistance or adhesion.

Basic Information

Product Name	Diethyl Chlorophosphite
CAS No.	589-57-1
Molecular Formula	C4H10ClO2P
Molecular Weight	156.55 g/mol
Synonyms	Chlorodiethoxophosphine; Diethoxyphosphinous Chloride; Phosphorochloridous Acid Diethyl Ester; Diethyl Phosphorochloridite; O,O-Diethyl Chlorophosphite; Ethyl Chlorophosphite; NSC 88110
EINECS	209-653-1

Quality Control

Our Diethyl Chlorophosphite is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous demands of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat and incompatible materials. Due to its hygroscopic and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 97.0%
Density (at 20°C)	1.080 - 1.090 g/mL
Refractive Index (n20D)	1.425 - 1.435
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.