Description

L-Cystine Diethyl Ester Dihydrochloride is a protected derivative of the amino acid L-cystine, widely used as a key synthetic intermediate in organic and peptide chemistry. Its primary value lies in providing a reactive, solubilized form of cystine for controlled chemical synthesis while protecting the disulfide bond and amine functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity building blocks for drug discovery, peptide synthesis, and biochemical research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those containing disulfide bridges or cysteine moieties.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate protected cystine residues into peptide chains.
• Biochemical Research: Serves as a precursor for preparing cysteine derivatives, enzyme substrates, and other biochemical probes for metabolic and proteomic studies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, chiral auxiliaries, and advanced organic compounds requiring high stereochemical purity.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	L-Cystine Diethyl Ester Dihydrochloride
CAS No.	583-89-1
Molecular Formula	C10H22Cl2N2O4S2
Molecular Weight	369.33 g/mol
Synonyms	L-Cystine diethyl ester dihydrochloride; Diethyl L-cystine dihydrochloride; Cystine diethyl ester hydrochloride; L-Cystine diethyl ester HCl; Bis(2-ethoxycarbonyl-1-aminoethyl) disulfide dihydrochloride; (R,R)-2,2'-Disulfanediylbis(3-ethoxy-3-oxopropan-1-aminium) dichloride; H-Cys(OEt)-Cys(OEt)-OH•2HCl
EINECS	209-516-5

Quality Control

Our L-Cystine Diethyl Ester Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.