Description

8-Ethoxycaffeine is a specialized alkylated xanthine derivative, structurally related to caffeine, with the CAS number 577-66-2. This compound is valued for its role as a key intermediate and reference standard in advanced pharmaceutical research and biochemical studies. It is primarily sought by R&D teams and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and conducting metabolic pathway investigations.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel adenosine receptor antagonists and other pharmacologically active molecules.
• Biochemical Research: Used as a reference standard and tool compound in studies of cytochrome P450 enzyme activity and drug metabolism.
• Neuroscience Studies: Employed in research exploring the structure-activity relationships of xanthine derivatives on the central nervous system.
• Analytical Reference Standard: Serves as a high-purity calibrant for HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Fine Chemical Synthesis: An intermediate for creating more complex, functionally modified caffeine analogs for specialized applications.

Basic Information

Product Name	8-Ethoxycaffeine
CAS No.	577-66-2
Molecular Formula	C10H14N4O3
Molecular Weight	238.24 g/mol
Synonyms	1,3,7-Trimethyl-8-ethoxyxanthine; 8-Ethoxy-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione; 8-Ethoxytheophylline; NSC 52326; ETX
EINECS	Contact for details

Quality Control

Our 8-Ethoxycaffeine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including identity confirmation by IR spectroscopy and purity determination by HPLC, to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming batch-specific results for purity, appearance, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.