Description

2-Nitro-4-(Trifluoromethyl)Benzenesulfonamide is a specialized organic intermediate featuring a sulfonamide functional group substituted with both nitro and trifluoromethyl moieties. This unique molecular structure makes it a valuable building block for the synthesis of more complex molecules, particularly in advanced chemical research and development. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring sulfonamide or trifluoromethyl groups for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the nitro and trifluoromethyl groups can contribute to pesticidal efficacy.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies and the discovery of new compounds.
• Dye and Pigment Intermediate: Can be utilized in the production of specialized dyes and pigments, leveraging the nitro group's chromophoric properties.
• Ligand and Catalyst Development: The sulfonamide group can act as a coordinating site in the design of novel ligands for catalytic systems.

Basic Information

Product Name	2-Nitro-4-(Trifluoromethyl)Benzenesulfonamide
CAS No.	577-61-7
Molecular Formula	C7H5F3N2O4S
Molecular Weight	270.18 g/mol
Synonyms	4-(Trifluoromethyl)-2-nitrobenzenesulfonamide; 2-Nitro-α,α,α-trifluoro-p-toluenesulfonamide; Benzenesulfonamide, 2-nitro-4-(trifluoromethyl)-; NSC 403697; p-Trifluoromethyl-o-nitrobenzenesulfonamide; α,α,α-Trifluoro-2-nitro-4-methylbenzenesulfonamide
EINECS	Contact for details

Quality Control

Our 2-Nitro-4-(Trifluoromethyl)Benzenesulfonamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics are provided with every shipment. We support custom purity requirements for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.