Description

(1R,9Ar)-Octahydro-2H-Quinolizine-1α-Carboxylic Acid CAS NO 574-99-2 is a chiral, bicyclic organic acid that serves as a sophisticated building block in advanced organic synthesis. Its rigid, fused ring structure and defined stereochemistry make it a valuable precursor for constructing complex molecules with high precision. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of alkaloids, antiviral agents, and other bioactive molecules requiring a defined quinolizidine scaffold.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where its bicyclic structure contributes to target specificity.
• Asymmetric Catalyst Ligand Precursor: Its chiral centers can be utilized to develop novel ligands for asymmetric hydrogenation and other catalytic transformations.
• Academic & R&D: Serves as a standard or starting material in methodological chemistry research focused on heterocyclic and natural product synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances.

Basic Information

Product Name	(1R,9Ar)-Octahydro-2H-Quinolizine-1α-Carboxylic Acid
CAS No.	574-99-2
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	(1R,9aR)-Octahydro-2H-quinolizine-1-carboxylic acid; (1R,9aR)-1,2,3,4,6,7,8,9a-Octahydroquinolizine-1-carboxylic acid; (-)-Octahydro-2H-quinolizine-1-carboxylic acid; L-Quinolizidine-1-carboxylic acid; (1R,9aR)-Decahydroquinoline-1-carboxylic acid; Quinolizidine-1-carboxylic acid (stereospecific); (1R,9aR)-1-Azabicyclo[4.3.0]nonane-1-carboxylic acid
EINECS	209-377-4

Quality Control

Our (1R,9Ar)-Octahydro-2H-Quinolizine-1α-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request, providing full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.