Description

4,5-Imidazoledicarboxylic Acid is a versatile heterocyclic dicarboxylic acid building block of significant importance in organic synthesis and pharmaceutical research. Its unique imidazole core functionalized with two carboxylic acid groups makes it a valuable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of purine analogs, histamine H3 receptor antagonists, and other nitrogen-containing heterocycles with potential therapeutic applications.
• Ligand Synthesis: Used in the preparation of chelating ligands for metal-organic frameworks (MOFs) and coordination chemistry due to its multiple coordination sites.
• Agrochemical Research: Serves as a building block for developing novel fungicides, herbicides, and plant growth regulators.
• Biochemical Research: Employed in studies related to nucleotide metabolism and as a precursor for fluorescent probes and biomarkers.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating functional polymers with imidazole groups, useful for ion-exchange or catalytic materials.
• Fine Chemical Synthesis: A versatile starting material for the preparation of various imidazole derivatives, including ionic liquids and corrosion inhibitors.

Basic Information

Item	Details
Product Name	4,5-Imidazoledicarboxylic Acid
CAS No.	570-22-9
Molecular Formula	C5H4N2O4
Molecular Weight	156.10 g/mol
Synonyms	1H-Imidazole-4,5-dicarboxylic acid; Imidazole-4,5-dicarboxylic acid; 4,5-Dicarboxyimidazole; 4,5-Imidazoledicarboxylic acid; NSC 66400; 4,5-Imidazoledicarboxylic Acid (4,5-Dicarboxyimidazole); 4,5-Imidazoledicarboxylic acid (8CI)
EINECS	209-329-0

Quality Control

Our 4,5-Imidazoledicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. We provide detailed Certificates of Analysis (COA) with key parameters including assay (by HPLC), identification (IR), and impurity profiles. Specifications can be tailored to meet specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.