Description

Semicarbazide Hydrochloride is a key organic synthesis intermediate and analytical reagent, primarily used for the preparation of semicarbazones from carbonyl compounds. Its high reactivity and specificity make it an essential building block in pharmaceutical research and fine chemical manufacturing. This compound is critical for researchers and industrial chemists in the pharmaceutical, agrochemical, and analytical chemistry sectors who require a reliable reagent for carbonyl derivatization and heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: Used in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing hydrazine or semicarbazide moieties.
• Analytical Chemistry Reagent: Employed for the derivatization and identification of aldehydes and ketones via semicarbazone formation, facilitating their analysis by chromatography or spectroscopy.
• Organic Synthesis Building Block: Serves as a precursor for the synthesis of heterocyclic compounds, including triazoles and other nitrogen-containing rings.
• Biochemical Research: Utilized in proteomics and biochemistry for protein modification studies and as an inhibitor of certain enzymes like copper-containing amine oxidases.
• Agrochemical Synthesis: Acts as an intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Can be used in the modification of polymers or as a cross-linking agent in specific resin systems.

Basic Information

Product Name	Semicarbazide Hydrochloride
CAS No.	563-41-7
Molecular Formula	CH6ClN3O
Molecular Weight	111.53 g/mol
Synonyms	Aminourea Hydrochloride; Carbamylhydrazine Hydrochloride; Hydrazinecarboxamide Hydrochloride; Semicarbazide HCl; Semicarbazide Monohydrochloride; Urea, 1-Amino-, Monohydrochloride; 1-Aminourea Hydrochloride
EINECS	209-247-4

Quality Control

Our Semicarbazide Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Melting Point	173 - 178 °C (decomposes)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.