Description

3,4-Dihydroquinolin-2(1H)-One (CAS NO 553-03-7) is a versatile heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its fused quinoline-lactam structure makes it a valuable intermediate for creating complex molecules with significant biological and material science applications. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various alkaloids, bioactive quinoline derivatives, and potential drug candidates targeting neurological and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that leverage the quinoline scaffold.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for constructing electron-transporting or emitting layers in organic electronic devices due to its rigid, planar structure.
• Coordination Chemistry & Ligand Design: Acts as a ligand or a precursor for N,O-donor ligands in catalytic systems and metal-organic frameworks (MOFs).
• Dye and Pigment Industry: Utilized as an intermediate for synthesizing specialized quinoline-based dyes and colorants.
• Academic & Contract Research: Employed in organic chemistry research for methodology development, heterocycle synthesis, and exploring new chemical spaces.

Basic Information

Product Name	3,4-Dihydroquinolin-2(1H)-One
CAS No.	553-03-7
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	2-Quinolinone, 3,4-dihydro-; 1,2,3,4-Tetrahydro-2-quinolinone; 2-Hydroxy-1,2,3,4-tetrahydroquinoline; 3,4-Dihydro-2(1H)-quinolinone; 2-Oxo-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydroquinolin-2-one; Carbostyril (less specific); Contact for additional trade names.
EINECS	209-043-6

Quality Control

Our 3,4-Dihydroquinolin-2(1H)-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, impurity profile, and physical characteristics. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.