Description

(2R)-3β-Ethyl-1,3,4,6,7,11Bβ-Hexahydro-9,10-Dimethoxy-2H-Benzo[A]Quinolizine-2α-Acetaldehyde CAS NO 549-91-7 is a complex, chiral benzo[a]quinolizine derivative, a key synthetic intermediate and scaffold in advanced organic chemistry. Its value lies in its intricate molecular architecture, which serves as a versatile building block for the synthesis of pharmacologically active compounds, particularly in alkaloid chemistry. This high-purity intermediate is essential for research and development laboratories in the pharmaceutical and fine chemical industries focused on creating novel therapeutic agents and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex alkaloids and potential drug candidates targeting neurological and cardiovascular systems.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies and for the development of new chemical libraries for high-throughput screening.
• Asymmetric Synthesis: Serves as a sophisticated starting material or intermediate in stereoselective synthesis routes due to its defined (2R) configuration.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high structural complexity.
• Academic & Institutional R&D: Utilized in universities and research institutes for studying heterocyclic chemistry, reaction mechanisms, and natural product synthesis.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2R)-3β-Ethyl-1,3,4,6,7,11Bβ-Hexahydro-9,10-Dimethoxy-2H-Benzo[A]Quinolizine-2α-Acetaldehyde
CAS No.	549-91-7
Molecular Formula	C₁₉H₂₇NO₃
Molecular Weight	317.42 g/mol
Synonyms	(2R)-3β-Ethyl-1,3,4,6,7,11bβ-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizine-2α-acetaldehyde; 2α-[(2R)-3β-Ethyl-1,3,4,6,7,11bβ-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]acetaldehyde; Benzo[a]quinolizine-2α-acetaldehyde derivative; (R)-3-Ethyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizine-2-acetaldehyde; Tetrahydroprotoberberine aldehyde analog
EINECS	Contact for details

Quality Control

Our (2R)-3β-Ethyl-1,3,4,6,7,11Bβ-Hexahydro-9,10-Dimethoxy-2H-Benzo[A]Quinolizine-2α-Acetaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure identity, purity, and enantiomeric excess meet exacting standards for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.