Description

(8Alpha,9R)-6'-Methoxycinchonan-9-Ol Monohydroiodide CAS NO 549-50-8 is a high-purity cinchona alkaloid derivative, specifically the hydroiodide salt of quinidine. This compound is valued for its role as a chiral selector and resolving agent in asymmetric synthesis and analytical chemistry. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in stereochemistry and catalysis research.

Application

• Chiral Resolution Agent: Used for the separation of enantiomers in preparative and analytical chromatography.
• Asymmetric Synthesis Catalyst: Acts as an organocatalyst or chiral ligand in stereoselective chemical reactions.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those with antimalarial or antiarrhythmic activity.
• Analytical Standard: Employed as a reference standard in quality control (QC) and method development for HPLC and other analytical techniques.
• Biochemical Research: Used in studies of ion channels and other biological systems due to its pharmacological properties.
• Fine Chemical Synthesis: A precursor for the synthesis of more complex chiral molecules in specialty chemical manufacturing.

Basic Information

Product Name	(8Alpha,9R)-6'-Methoxycinchonan-9-Ol Monohydroiodide
CAS No.	549-50-8
Molecular Formula	C₂₀H₂₇N₂O₂•HI
Molecular Weight	458.35 g/mol
Synonyms	Quinidine Hydroiodide; (8α,9R)-6'-Methoxycinchonan-9-ol Hydroiodide; Cinchonan-9-ol, 6'-methoxy-, monohydroiodide, (8α,9R)-; Quinidine Iodide; (8α,9R)-6'-Methoxy-α-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol Hydroiodide; β-Quinidine Hydroiodide; Conquinine Hydroiodide
EINECS	208-961-7

Quality Control

Our (8Alpha,9R)-6'-Methoxycinchonan-9-Ol Monohydroiodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Specific Rotation [α]²⁰D	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.